64bit computer?

I would like to hear what every one thinks about 64 bit computers. What
makes a 64bit computer? Is it just the OS and or does a 64bit computer
need a specific kind of motherboard and cpu? Any thing else I have left out?
I am assuming that applications have to run in 64bit mode or they don't
run at all.

I really would appreciate your view points.

Thanks

Mike Enriquez
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