I am currently use my ssd as the full drive on my laptop. A couple of things you need to know and the biggest one is to make sure that you are doing TRIM on all of the partitions (I think you add "disgard" to the options portions for the partitions in /etc/fstab). Regarding stability and reliability SSD's have come a long way and other then enabling TRIM on the drive they pretty much are the "same" as regular ssd's. Unless you are writing terrabytes of information per day SSD's will pretty much last just as long as platter hdd. I agree with David and see if you can do a hybrid drive. I have no experience with them as David has but from what I heard hybrid drives are great. Speaking of hybrid drives, maybe purchase a smaller ssd make it your root partition and use a platter hdd for your home. That way you can get the best of both worlds. Keep in mind that most of your files are not per say the bottle neck of your application loading (ie if you are opening up your document file, the loading of the file is not as bad as loading libre office itself). One thing to note with hybrid drives is to make sure that the height of them will be compatible. I have a thinkpad x230 and it will not support the standard height of 9mm.