I have done various implementa6tions from FC and Fedora to CentOs and RHEL and back.

Packages can be vastly different since Fedora Core and Fedora are cutting edge type innovations (not necessarily secure, etc.)  Depending on the use of the system, one must be very cautious, for isntance SSL (depending on your varsions).  There are often huge incompatibilities with yum in FC and Fedora - so one needs to be better with package management (same is true for CentOs).

Here's the official Redhat statements:

http://www.redhat.com/magazine/019may06/features/fedora_rhel_1/

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> Date: Tue, 13 Jan 2009 21:10:35 -0700
> Subject: starting with Fedora, moving to RHEL
> From: jjzeidner@gmail.com
> To: plug-discuss@lists.plug.phoenix.az.us
>
> Hello,
>
> has anyone built a system using Fedora, but then redeployed it to
> RHEL? Anything I should be aware of?
>
> -jmz
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