I don't have any personal experience with Exim having issues with sendmail
compatibility.  I do have anecdotal evidence from a friend who was using exim.

I have seen Qmail barf - but its been a few years.

Jeremy C. Reed spoke forth with the blessed manuscript:
> > Also, I just thought of something.  Exim & Qmail are not exactly Sendmail
> > compatible.  If you have something on your system that calls sendmail (the
> > binary), Exim and Qmail may not work properly.  Postfix is Sendmail
> > compatible, and won't break things.
> 
> Exim works fine as a generic "sendmail" command line tool replacement. In 
> my experience, I don't see how Postfix could be more compatible than Exim 
> to Sendmail.
> 
> Any examples? Or what is your definition of Sendmail compatible?
> 
> By the way, I wrote and use a sendmail command-line replacement called 
> mailout. I have used it for a few years as a sendmail alternative for 
> outbound email.
> 
>  Jeremy C. Reed
> 
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