"setserial /dev/ttyS? irq# portI/OADDRESS ^fourport ^auto_irq skip_test
autoconfig spd_vhi "
which gave the response :
"Cannot set serial info: Address already in use."

today I find the advise
"setserial /dev/ttyS3 port <address> irq <#> uart 16550A

But as it said before "Address already in use."